2012 | "α-MoO3 nanowire-based amperometric biosensor", Journal of Solid State…
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Title : α-MoO3 nanowire-based amperometric biosensor for L-lactate detection
Authors: Imran Shakir,Muhammad Shahid, Hyoung Woo Yang, Serhiy Cherevko, Chan-Hwa Chung, and Dae Joon Kang
Journal : Journal of Solid State Electrochem
Vol/No/Page : 16/6/2197-2201
DOI : 10.1007/s10008-012-1648-0
Abstract :
Large-scale orthorhombic single-crystalline molybdenum trioxide nanowires were synthesized using a facile one-pot hydrothermal method. Lactate oxidase enzyme was immobilized on the nanowires to produce a highly sensitive electrochemical biosensor for l-lactate detection. At an applied potential of 0.5 V, the sensor exhibited a high sensitivity of 0.87 mu A/mM with a fast response to l-lactate (90% of response times within 10 s). A linear response was obtained over a concentration range from 0.5 to 8 mM with a detection limit of 0.15 mM (S/N = 3). The developed biosensor showed excellent reproducibility and operational stability, as well as the ability to be stored long term.
Authors: Imran Shakir,Muhammad Shahid, Hyoung Woo Yang, Serhiy Cherevko, Chan-Hwa Chung, and Dae Joon Kang
Journal : Journal of Solid State Electrochem
Vol/No/Page : 16/6/2197-2201
DOI : 10.1007/s10008-012-1648-0
Abstract :
Large-scale orthorhombic single-crystalline molybdenum trioxide nanowires were synthesized using a facile one-pot hydrothermal method. Lactate oxidase enzyme was immobilized on the nanowires to produce a highly sensitive electrochemical biosensor for l-lactate detection. At an applied potential of 0.5 V, the sensor exhibited a high sensitivity of 0.87 mu A/mM with a fast response to l-lactate (90% of response times within 10 s). A linear response was obtained over a concentration range from 0.5 to 8 mM with a detection limit of 0.15 mM (S/N = 3). The developed biosensor showed excellent reproducibility and operational stability, as well as the ability to be stored long term.